By putting the most pressure on your opponents and reducing the number of points in your possession, a well-timed knock can guarantee victory. A thorough evaluation is required prior to making this crucial choice, though, as knocking too early or too late may have nmdm slots apkegative effects. Based on your opponents' discards & draws during the game, it's a good idea to assess not only your own hand but also the number of melds they may have created. You might want to think about knocking if you think you've made enough melds while keeping your remaining points low, preferably under 10. On the other hand, it might be wise to wait to knock until you feel more secure if there's a possibility that your opponent has already created several melds or has been intentionally drawing from the discard pile.